Hodgkin’s Disease Diagnosed in Third Trimester of Pregnancy

Hodgkin’s Disease (HD) is a neoplasia with bimodal peak at age 20-30 years and after age of 75. As it is well known as a young people disease it’s not rare to diagnose HD in pregnant women. Its incidence in pregnant population is estimated to be 1 per 34000 live births. Several studies have shown that pregnancy doesn’t get worsen the prognosis of disease. Presentation as cholestatic febrile illness, with subsequent diagnosis of HD, has been reported sporadically. About 25% of cholestasis in HD patients has no histological signs of direct liver involvement or extrahepatic obstruction. Possible mechanisms of such intrahepatic cholestasis include a paraneoplastic effect and the vanishing bile-duct syndrome.